I recently had a question regarding some changes that took place in the 2009 edition of the United States Pharmacopoeia. In USP 32, General Chapter 621 (1), the adjustments allowed to meet system suitability for liquid chromatography (LC) methods include a change in column internal diameter of ±25%. A change was made in USP 32 Supplement 2 (2).
Journal:
LCGC North America, Feb 1, 2010
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